Mar 01, 2020 · Positive surgical margins in cancer patients are commonly associated with worse prognosis and a higher risk of secondary treatment. However, its role in patients undergoing radical prostatectomy remains controversial since only 30%35% and 19%48% of men with positive surgical margins develop metastatic disease or biochemical recurrence after radical prostatectomy,
Extent of positive surgical margins following radical May 15, 2019 · The presence of positive surgical margins (PSM) following radical prostatectomy (RP) is a worrying for surgeons and patients alike as it represents an independent biochemical recurrence (BR) risk factor [ 1, 2, 3, 4, 5, 6, 7, 8 ]. The rate of PSM is 530% for organ-confined prostate cancer and 1765% for locally-advanced cancer [ 9, 10, 11 ].
AbstractIntroductionMethodsResultsConclusionA positive surgical margin at prostatectomy is defined as tumor cells touching the inked edge of the specimen. This finding is reported in 8.8% to 42% of cases (median about 20%) in various studies. It is one of the main determinants of eventual biochemical (PSA) failure, generally associated with a doubled or tripled risk of failure. The effect of a positive margin on outcome can be modified by stage or grade and the length, number and location of positive margins, as well as by technical operative approach and durDoes Gleason score of positive surgical margin after Introduction:Positive surgical margins (PSM) in cancer patients are commonly associated with worse prognosis and a higher risk of secondary treatment. However, the relevance of this parameter in prostate cancer patients undergoing radical prostatectomy (RP) remains controversial, given the inconsistencies in its ability to predict biochemical recurrence (BCR) and oncological outcomes.
Frequency of Positive Surgical Margin at Prostatectomy and Jun 09, 2011 · 1.1. Definition of a Positive Surgical Margin (PSM) in Radical Prostatectomy Specimens. As with all surgical specimens resected for cancer, the margins of a prostatectomy specimen are inked, usually using one color dye for the right side and one for the left.Positive surgical margins at radical prostatectomy predict Jun 01, 2010 · Positive surgical margins (PSM) in men undergoing radical prostatectomy (RP) for prostate cancer (PCa) are associated with an increased risk of biochemical recurrence. Little data have evaluated the role of PSM in PCa-specific mortality (PCSM).